Fetal pleural effusion

Prenat Diagn. 2007 Sep;27(9):793-9. doi: 10.1002/pd.1768.


Fetal pleural effusion, a nonspecific accumulation of fluid in the pleural space, is an uncommon anomaly which can be associated with aneuploidy and a range of other structural malformations or genetic syndromes. Spontaneous resolution is not rare and confers a good prognosis. Perinatal outcome is better for those fetuses without hydrops than those presenting with hydrops. A detailed review of the literature indicates that, for fetuses with persistent effusions, in utero intervention (repeated thoracocentesis, intrauterine shunting and pleurodesis) may improve the chances of survival.

Publication types

  • Evaluation Study
  • Review

MeSH terms

  • Algorithms
  • Disease Progression
  • Fetal Diseases / diagnosis*
  • Fetal Diseases / etiology*
  • Fetal Diseases / pathology
  • Fetoscopy / methods
  • Humans
  • Paracentesis
  • Pleural Effusion / complications
  • Pleural Effusion / diagnosis*
  • Pleural Effusion / etiology*
  • Pleural Effusion / therapy
  • Pleurodesis / methods
  • Thoracic Surgery, Video-Assisted / methods