[Carnosine--biological activity and perspectives in pharmacotherapy]
- PMID: 17607973
[Carnosine--biological activity and perspectives in pharmacotherapy]
Abstract
This review summarizes the data on biological activity and therapeutic potential of camosine. Camosine is a naturally occurring, water-soluble dipeptide. It has buffering activities in excitable animal and human tissues, exhibits metal ions binding properties, antioxidant and antiglycating properties, extends the life-span of cultured human diploid cells, regulates sarcoplasmic reticulum Ca-release channel activity. Carnosine may be a potential therapeutic agent (neurodegenerative, metabolic, cardiovascular diseases) mainly due to its antioxidant and antiglycating activities.
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