Cell competition: the embrace of death

Dev Cell. 2007 Jul;13(1):1-2. doi: 10.1016/j.devcel.2007.06.002.

Abstract

Cell competition compares cells within a growing population and eliminates the weaker ones by apoptosis. In a recent issue of Cell, Li and Baker (2007) show in the Drosophila wing disc that cells fated to die induce in neighboring cells the activity of engulfment genes, whose function is essential to complete the apoptotic program.

Publication types

  • Review

MeSH terms

  • Animals
  • Apoptosis / physiology*
  • Drosophila / growth & development*
  • Gene Expression Regulation, Developmental*