Telomeres in the rice blast fungus Magnaporthe oryzae: the world of the end as we know it

FEMS Microbiol Lett. 2007 Aug;273(2):125-32. doi: 10.1111/j.1574-6968.2007.00812.x. Epub 2007 Jul 4.


The subtelomeres of many microbial eukaryotes are highly enriched in genes with roles in niche adaptation. Host and cultivar specificity genes in the rice blast fungus Magnaporthe oryzae also tend to be located near telomeres. In addition, the M. oryzae telomeres are highly variable chromosome regions. These observations suggested that plant pathogenic fungi might also use subtelomere regions for the amplification of genes with adaptive significance. Targeted sequencing of the M. oryzae telomeres provided an opportunity to test this hypothesis, and has yielded valuable insights into the organization and dynamics of these important chromosome regions.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Chromosomal Instability
  • Chromosomes, Fungal
  • DNA Helicases / genetics
  • Gene Rearrangement
  • Genes, Fungal
  • Magnaporthe / genetics*
  • Magnaporthe / isolation & purification
  • Magnaporthe / pathogenicity
  • Oryza / microbiology
  • Retroelements / physiology
  • Sequence Analysis, DNA
  • Telomere / chemistry
  • Telomere / physiology*


  • Retroelements
  • DNA Helicases