Celiac disease: association with adult-onset Still's disease: apropos of a clinical case

Indian J Med Sci. 2007 Jul;61(7):414-7.


Adult-onset Still's disease (AOSD) is a rheumatic disorder of unknown etiology characterized by a triad of fever, polyarthritis and evanescent rash. We present a case report of a 28-year-old female who presented with complaints of fever, joint pains, rash, weakness for the past 4 years and diarrhea for the past 2 years. On investigation the patient was diagnosed to be a case of AOSD. Duodenal biopsy report was suggestive of celiac disease with a positive IgA tissue transglutaminase and anti-endomysial antibody. The patient was started on weekly methotrexate and gluten-free diet and her symptoms gradually improved. The patient remains in our follow-up and is doing well.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Autoimmune Diseases
  • Celiac Disease / diagnosis*
  • Celiac Disease / genetics
  • Celiac Disease / physiopathology
  • Female
  • Genetic Predisposition to Disease
  • Humans
  • Immunoglobulin A
  • Methotrexate
  • Risk Factors
  • Still's Disease, Adult-Onset / diagnosis*
  • Still's Disease, Adult-Onset / genetics
  • Still's Disease, Adult-Onset / physiopathology


  • Immunoglobulin A
  • Methotrexate