Extranodal type T/NK-cell lymphoma with an atypical clinical presentation

Pediatr Hematol Oncol. 2007 Jun;24(4):291-9. doi: 10.1080/08880010701441112.

Abstract

Peripheral-type natural killer (NK)- or T-cell lymphomas are rare disorders characterized with clonal proliferation of mature lymphocytes. They have been linked to chronic and active Epstein-Barr virus infection (CAEBV), which itself is not defined as a malignant hematological disorder. The authors present a patient with T/NK-cell lymphoma involving skin, kidneys, spleen, pancreas, and meninges. She was remarkable for having the mosaic feature of more than one type of extranodal T/NK-cell lymphoma. She also had mixed findings of CAEBV that might have been attributed both to hypersensitivity to mosquito bites and to hemophagocytic lymphohistiocytosis.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Clone Cells / pathology
  • Epstein-Barr Virus Infections
  • Female
  • Humans
  • Killer Cells, Natural / pathology*
  • Lymphoma, T-Cell / pathology*
  • Tissue Distribution