This study aimed to examine the reliability and validity of clinician-rated psychiatric scales for end-stage renal disease (ESRD) patients undergoing hemodialysis (HD) treatment in Turkey. For this, the Hamilton Depression Rating Scale (HDRS), Hamilton Anxiety Rating Scale (HARS), Global Assessment of Functioning (GAF) Scale, Clinical Global Impression (CGI) Scale, and Mini Mental State Exam (MMSE) were administered to 45 ESRD outpatients undergoing HD treatment. Regarding the reliability of HDRS and HARS, internal consistency and split-half reliability analyses revealed acceptable coefficients. The test - retest reliability coefficients were also examined for all measures after a period of a month, and despite this relatively long time interval, test - retest reliability coefficients were above .60 for all measures. Concerning the validity studies, all these scales revealed suitable convergent, discriminant, and criterion validity outcomes. A cut-off point of 10 for HDRS is suggested for the identification of depression in this population. In general, the findings of this study indicate that HDRS, HARS, CGI, GAF, and MMSE are reliable and valid instruments that can be used among ESRD patients undergoing HD.