10-year follow-up study of epilepsy with psychosis

Jpn J Psychiatry Neurol. 1991 Jun;45(2):360-1. doi: 10.1111/j.1440-1819.1991.tb02488.x.


Thirty-three cases of psychosis associated with epilepsy were followed in our clinic for 10 years. In 12 cases, the psychotic symptom appeared episodically and 9 of them had more than one relapse and 7 of them more than 2 relapses. Only 3 cases had no relapse. In 21 cases, the psychotic symptoms were continuous, lasting more than 2 years. In 8 of them, the symptoms were stable and remained unchanged but in 13 of them, the symptom showed exacerbation and partial remissions. In 11 cases, a decrease or discontinuation of antipsychotic drugs (mostly haloperidol) significantly provoked or aggravated the psychotic symptoms.

MeSH terms

  • Adult
  • Epilepsy / psychology*
  • Female
  • Follow-Up Studies
  • Hallucinations / psychology
  • Humans
  • Male
  • Middle Aged
  • Neurocognitive Disorders / psychology*
  • Recurrence
  • Schizophrenia, Paranoid / psychology