Adult cystatin C reference intervals determined by nephelometric immunoassay

Clin Biochem. 2007 Sep;40(13-14):1084-7. doi: 10.1016/j.clinbiochem.2007.05.011. Epub 2007 Jun 8.


Objective: The aim of this study was to determine the adult reference values for cystatin C (CysC) and to evaluate their consistence with those reported in the literature.

Design and methods: CysC was analyzed in a consecutive series of subjects (100 males and 100 females) by a nephelometric immunoassay. Medline was searched for CysC reference values.

Results: CysC reference intervals showed 4-11% of variation at the upper limit. The mean upper limit was </=1.0 mg/L of CysC.

Conclusion: Nephelometric CysC reference intervals are consistent among different populations.

MeSH terms

  • Adolescent
  • Adult
  • Cystatin C
  • Cystatins / analysis*
  • Female
  • Humans
  • Immunoassay / methods*
  • Male
  • Nephelometry and Turbidimetry / methods*
  • Reproducibility of Results


  • CST3 protein, human
  • Cystatin C
  • Cystatins