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Review
. 2007 Aug;19(4):350-4.
doi: 10.1097/GCO.0b013e32821642d1.

Elective Oophorectomy in the Gynecological Patient: When Is It Desirable?

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Review

Elective Oophorectomy in the Gynecological Patient: When Is It Desirable?

William H Parker et al. Curr Opin Obstet Gynecol. .

Abstract

Purpose of review: Oophorectomy is electively performed in approximately 300,000 US women per year who are having hysterectomy for benign disease.

Recent findings: New studies have suggested that elective oophorectomy may not be advisable for the majority of women, as it may lead to a higher risk of death from cardiovascular disease and hip fracture, and may result in a higher incidence of dementia and Parkinson's disease. Women with known BRCA 1/2 germ-line mutations clearly benefit from oophorectomy after childbearing.

Summary: Prophylactic oophorectomy should be undertaken with caution in the majority of women with an average risk of ovarian cancer who are having a hysterectomy for benign disease.

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