Gastric metastases from conjunctival melanoma

Melanoma Res. 2007 Aug;17(4):255-6. doi: 10.1097/CMR.0b013e3281c4a056.


The aim of the study is to discuss the pattern and risk factors for metastatic disease in conjunctival melanoma. We draw comparisons with cutaneous metastatic melanoma. We describe the clinical course of a patient with recurrent conjunctival melanoma in the context of primary acquired melanosis with atypia. The local disease was eventually treated with a lid splitting exenteration. The patient suffered from an isolated distant metastasis to the gastric wall that was managed by partial gastrectomy. Conjunctival melanoma has many similarities with its cutaneous counterpart. In both conditions the regional lymph nodes are the most common site for metastases, however, isolated distant metastases can occur. Gastric metastases are frequently seen in cutaneous melanoma. This is the first report of an isolated gastric metastasis from a conjunctival melanoma.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aged, 80 and over
  • Binding Sites
  • Biopsy
  • Conjunctival Neoplasms / diagnosis*
  • Conjunctival Neoplasms / metabolism*
  • Conjunctival Neoplasms / pathology
  • Gastrectomy
  • Humans
  • Immunohistochemistry
  • Male
  • Melanoma / diagnosis*
  • Melanoma / metabolism
  • Melanoma / pathology*
  • Mitosis
  • Neoplasm Metastasis
  • Stomach Neoplasms / secondary*
  • Treatment Outcome
  • Uveal Neoplasms / diagnosis*
  • Uveal Neoplasms / pathology*