O-aryloxycarbonyl hydroxamates: new beta-lactamase inhibitors that cross-link the active site

J Am Chem Soc. 2007 Aug 8;129(31):9548-9. doi: 10.1021/ja072370u. Epub 2007 Jul 12.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Binding Sites
  • Cross-Linking Reagents / chemistry*
  • Crystallography, X-Ray
  • Enterobacter cloacae / enzymology
  • Enzyme Inhibitors / chemistry*
  • Enzyme Inhibitors / pharmacology*
  • Hydroxamic Acids / chemistry*
  • Models, Molecular
  • Molecular Structure
  • beta-Lactamase Inhibitors*
  • beta-Lactamases / chemistry*
  • beta-Lactamases / metabolism

Substances

  • Cross-Linking Reagents
  • Enzyme Inhibitors
  • Hydroxamic Acids
  • beta-Lactamase Inhibitors
  • beta-Lactamases