A randomized comparison of different methods of analgesia in abortion using manual vacuum aspiration

Int J Gynaecol Obstet. 2007 Nov;99(2):91-4. doi: 10.1016/j.ijgo.2007.05.023. Epub 2007 Jul 12.


Objective: To estimate the effectiveness of different methods of analgesia among women treated with manual vacuum aspiration for spontaneous abortion.

Materials and methods: The 113 patients diagnosed with incomplete abortion and considered candidates for manual vacuum aspiration were randomly assigned to 3 groups of analgesic administration: diclofenac plus paracervical block; meperidine plus diclofenac; and meperidine alone. Pain levels were evaluated using the Wong Scale of Pain.

Results: The mean pain scores for the three groups were: diclofenac and paracervical block 5.4; meperidine plus diclofenac 5.0; meperidine 5.7 (P=0.57). Analysis of pain using the levels mild (0-3), moderate (4-6), and severe (7-10) showed no statistical significance among the 3 groups of analgesics. Adverse effects were more common in the groups using analgesia containing meperidine.

Conclusions: There was no significant difference between the analgesics used among the 3 groups. Most of the patients, regardless of the analgesic used, reported moderate pain.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Abortion, Incomplete / etiology
  • Abortion, Incomplete / surgery*
  • Adult
  • Analgesia, Obstetrical*
  • Anesthesia, Obstetrical / methods*
  • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Diclofenac / administration & dosage
  • Diclofenac / therapeutic use*
  • Female
  • Humans
  • Meperidine / administration & dosage
  • Meperidine / therapeutic use*
  • Pain / prevention & control*
  • Vacuum Extraction, Obstetrical / adverse effects*


  • Anti-Inflammatory Agents, Non-Steroidal
  • Diclofenac
  • Meperidine