Relationship between the serum concentrations of serotonin and lipids and aggression in dogs

Vet Rec. 2007 Jul 14;161(2):59-61. doi: 10.1136/vr.161.2.59.


The serum concentrations of serotonin and lipids--triglycerides, total cholesterol, low density lipoprotein, high density lipoprotein and very low density lipoprotein--were determined in 18 normal dogs and 23 dogs diagnosed as aggressive on the basis of interviews with their owners and an assessment of their behaviour with reference to a canine overt aggression chart. The serum serotonin levels in the aggressive dogs were significantly lower than in the normal dogs (P<0.01), but the differences in serum lipids between the two groups were not statistically significant.

MeSH terms

  • Aggression*
  • Animals
  • Behavior, Animal / physiology*
  • Case-Control Studies
  • Cholesterol / blood
  • Dog Diseases / blood
  • Dog Diseases / psychology*
  • Dogs
  • Female
  • Lipids / blood*
  • Male
  • Serotonin / blood*
  • Triglycerides / blood


  • Lipids
  • Triglycerides
  • Serotonin
  • Cholesterol