A novel actinomycete, strain HMC10(T), was isolated from a soil sample taken from the banks of the Gamka River in the Swartberg Nature Reserve, Western Cape Province, South Africa. Strain HMC10(T) was identified as a member of the genus Nonomuraea by a polyphasic approach. Strain HMC10(T) could be differentiated from other members of the genus Nonomuraea on the basis of physiology and 16S rRNA gene sequence analysis. DNA-DNA hybridization further differentiated strain HMC10(T) from its nearest phylogenetic neighbour, Nonomuraea turkmeniaca NRRL B-16246(T) (4.5 +/- 3.8% DNA relatedness). Strain HMC10(T) exhibited weak antibiosis against Mycobacterium aurum A+, but none against Mycobacterium tuberculosis H37Rv(T). The name Nonomuraea candida is proposed, with the type strain HMC10(T) (= DSM 45086(T) = NRRL B-24552(T)).