Randomized clinical trial of LigaSure and conventional diathermy haemorrhoidectomy

Br J Surg. 2007 Aug;94(8):937-42. doi: 10.1002/bjs.5904.


Background: The aim of this randomized prospective trial was to compare LigaSure and conventional diathermy haemorrhoidectomy.

Methods: Two hundred and eighty-four patients with grade III or IV haemorrhoids were randomized to LigaSure or diathermy (Milligan-Morgan) haemorrhoidectomy as a day-case procedure. Operating time, postoperative pain score, hospital stay, postoperative complications, wound healing time and time to return to normal activities were assessed. Thirty-four patients were lost to follow-up.

Results: The mean operating time for LigaSure haemorrhoidectomy was significantly shorter than that for diathermy (P = 0.011). Patients treated with LigaSure had significantly less postoperative pain (measured on a visual analogue scale; P = 0.010), a shorter wound healing time (defined as time to absence of swelling; P = 0.012) and less time off work (P = 0.010) than patients who had diathermy. Neither postoperative complications nor mean hospital stay (day-case surgery) were significantly different.

Conclusion: LigaSure haemorrhoidectomy demonstrates simplicity, reproducibility, a low complication rate, fast wound healing, a quick return to work and reduced postoperative pain.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Ambulatory Surgical Procedures
  • Analysis of Variance
  • Diathermy / methods*
  • Female
  • Hemorrhoids / therapy*
  • Humans
  • Length of Stay
  • Ligation / methods
  • Male
  • Middle Aged
  • Pain, Postoperative / etiology
  • Postoperative Hemorrhage / etiology
  • Prospective Studies
  • Wound Healing / physiology