Efficacy of Slim339 in reducing body weight of overweight and obese human subjects

Phytother Res. 2007 Dec;21(12):1177-81. doi: 10.1002/ptr.2231.


A double-blind, randomized, parallel-group, placebo-controlled study has been carried out in order to evaluate the effect of orally self-administered Slim339, a proprietary fixed combination of Garcinia cambogia extract with calcium pantothenate (standardized for the content of hydroxycitric acid and pantothenic acid) and extracts of Matricaria chamomilla, Rosa damascena, Lavandula officinalis and Cananga odorata, on body weight in overweight and obese volunteers. During a 60-day treatment period, the average reduction in body weight for the group receiving Slim339 (n = 30) was 4.67% compared with 0.63% for the placebo group (n = 28) (p < 0.0001). Weight losses of >or=3 kg were recorded for 23 subjects in the treatment group and only one in the placebo group. It is concluded that Slim339 represents a potential therapy for obesity.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-Obesity Agents / therapeutic use*
  • Body Weight / drug effects*
  • Double-Blind Method
  • Female
  • Garcinia cambogia
  • Humans
  • Male
  • Middle Aged
  • Obesity / drug therapy*
  • Pantothenic Acid / pharmacology
  • Pantothenic Acid / therapeutic use*
  • Phytotherapy*
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use*


  • Anti-Obesity Agents
  • Plant Extracts
  • Slim339
  • Pantothenic Acid