Vaginal superficial myofibroblastoma. Case report and review of the literature

Rom J Morphol Embryol. 2007;48(2):165-70.


Superficial myofibroblastoma of the lower female genital tract is a rare, recently described tumor, which has a distinctive clinico-pathological profile. We report a 63-year old patient who presented with a polypoid vaginal mass. Histopathological examination revealed a moderately cellular tumor composed of bland spindled and stellate cells. Immunohistochemical investigations showed reactivity for vimentin, desmin and CD34. This tumor should be differentiated from other mesenchymal lesions, which may arise in this area.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Desmin / metabolism
  • Female
  • Humans
  • Hyalin / metabolism
  • Middle Aged
  • Neoplasms, Muscle Tissue / diagnosis*
  • Neoplasms, Muscle Tissue / metabolism
  • Neoplasms, Muscle Tissue / pathology
  • Vaginal Neoplasms / diagnosis*
  • Vaginal Neoplasms / metabolism
  • Vaginal Neoplasms / pathology
  • Vimentin / metabolism


  • Desmin
  • Vimentin