Electrical detection of hepatitis C virus RNA on single wall carbon nanotube-field effect transistors

Tawab Dastagir; Erica S Forzani; Ruth Zhang; Islamshah Amlani; Larry A Nagahara; Raymond Tsui; Nongjian Tao

doi:10.1039/b707025j

Electrical detection of hepatitis C virus RNA on single wall carbon nanotube-field effect transistors

Analyst. 2007 Aug;132(8):738-40. doi: 10.1039/b707025j. Epub 2007 Jun 12.

Authors

Tawab Dastagir¹, Erica S Forzani, Ruth Zhang, Islamshah Amlani, Larry A Nagahara, Raymond Tsui, Nongjian Tao

Affiliation

¹ Department of Electrical Engineering, Arizona Institute for Nano-electronics, Arizona State University, Tempe, AZ 85287-5706, USA.

PMID: 17646871
DOI: 10.1039/b707025j

Abstract

We report the unambiguous detection of a sequence of Hepatitis C Virus (HCV) at concentrations down to the fractional pM range using Single Wall Carbon Nanotube (SWNT) Field Effect Transistor (FET) devices functionalized with Peptide Nucleic Acid (PNA).

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Electrochemistry / methods
Hepacivirus / genetics*
Microchemistry / methods
Nanotechnology
Nanotubes, Carbon*
Peptide Nucleic Acids
RNA, Viral / analysis*
Transistors, Electronic*

Substances

Nanotubes, Carbon
Peptide Nucleic Acids
RNA, Viral