Stability of executive function deficits into young adult years: a prospective longitudinal follow-up study of grown up males with ADHD

Acta Psychiatr Scand. 2007 Aug;116(2):129-36. doi: 10.1111/j.1600-0447.2007.01008.x.

Abstract

Objective: Although individuals with attention deficit-hyperactivity disorder (ADHD) commonly exhibit deficits in executive functions that greatly increase the morbidity of the disorder, all available information on the subject is cross sectional.

Method: Males (n = 85) 9-22 years with ADHD followed over 7 years into young adulthood were assessed on measures of sustained attention/vigilance, planning and organization, response inhibition, set shifting and categorization, selective attention and visual scanning, verbal and visual learning, and memory. A binary definition of executive function deficits (EFDs) was defined based on a subject manifesting at least two abnormal tests 1.5 standard deviations from controls.

Results: The majority of subjects maintained EFDs over time (kappa: 0.41, P < 0.001; sensitivity: 55%, specificity: 85%, positive predictive value: 69%, and negative predictive value: 75%).

Conclusion: Considering the morbidity of EFDs, these findings stress the importance of their early recognition for prevention and early intervention strategies. EFDs are stable over time.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Attention Deficit Disorder with Hyperactivity / diagnosis*
  • Attention Deficit Disorder with Hyperactivity / psychology
  • Attention*
  • Child
  • Discrimination Learning
  • Follow-Up Studies
  • Humans
  • Inhibition, Psychological*
  • Intelligence
  • Male
  • Mental Processes*
  • Mental Recall*
  • Neuropsychological Tests / statistics & numerical data
  • Pattern Recognition, Visual
  • Problem Solving*
  • Prospective Studies
  • Psychometrics
  • Psychomotor Performance
  • Verbal Learning