Oral and dental conditions of children with selective IgA deficiency

Pediatr Allergy Immunol. 2008 Feb;19(1):33-6. doi: 10.1111/j.1399-3038.2007.00575.x. Epub 2007 Jul 25.


Oral conditions in selective IgA deficiency in children have rarely been published. Our aims were to investigate their mucosal, periodontal, and cariological conditions in IgA deficient children matched with healthy controls and to draw data on their oral health in the North-East Region of Hungary. Thirty four patients and 111 healthy controls, matched by age and sex, were studied for oral mucosal disorders, periodontal disease, and caries. Mucosal diseases were found in 10 (29%) patients. The severity of periodontal lesions characterized by plaque index, gingival index and pocket depth (exceeding more than 3 mms) was similar in patients and controls. A significant difference was observed in caries experience of the primary, but not in the permanent dentition as assessed by the dmf/DMF-t/T; s/S system used universally to quantitate decayed, missing, and filled teeth and tooth surfaces both in primary (small letters) and in permanent (capital letters) dentitions. Patients with IgA deficiency had significantly higher dmft, and dmfs indices than controls, supporting the notion that children with selective IgA deficiency exhibit an increased risk for developing dental caries. However the severities of mucosal or periodontal disorders are comparable with that in the normal population.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Dental Caries / etiology*
  • Female
  • Humans
  • IgA Deficiency / complications*
  • Male
  • Mouth Mucosa / pathology*
  • Oral Health
  • Periodontal Diseases / etiology*