Examination of HIV-1 Protease Secondary Structure Specificity Using Conformationally Constrained Inhibitors

J Med Chem. 1991 Dec;34(12):3395-9. doi: 10.1021/jm00116a009.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Drug Design
  • HIV Protease / chemistry*
  • HIV Protease / metabolism
  • Models, Molecular
  • Molecular Sequence Data
  • Protease Inhibitors / chemical synthesis
  • Protease Inhibitors / chemistry*
  • Protease Inhibitors / metabolism
  • Protein Binding
  • Protein Conformation
  • Thermodynamics

Substances

  • Protease Inhibitors
  • HIV Protease