Bilateral subcutaneous fibrosarcomas in a cat following feline parvo-, herpes- and calicivirus vaccination

J Feline Med Surg. 2007 Oct;9(5):432-4. doi: 10.1016/j.jfms.2007.05.002. Epub 2007 Jul 30.


A crossbred cat developed a subcutaneous fibrosarcoma on the left side of the thorax at the site of previous administration of a feline parvo-, herpes- and calicivirus vaccine. A few months later the cat developed a second mass on the right side of the thorax after a booster vaccine had been administered at this site. This unique case of bilateral fibrosarcomas in a cat shortly after vaccination with parvo-, herpes- and caliciviruses suggests an individual disposition for the development of vaccine-associated sarcomas and a possible triggering of this type of pathological response which could have precipitated the development of the second tumour. To the authors' knowledge, this is the first case of vaccine-induced fibrosarcomas occurring bilaterally after injection of a feline parvo-, herpes- and calicivirus containing vaccine at different sides of the thorax.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Cat Diseases / blood
  • Cat Diseases / chemically induced*
  • Cat Diseases / diagnosis*
  • Cat Diseases / pathology
  • Cat Diseases / surgery
  • Cats
  • Diagnosis, Differential
  • Fibrosarcoma / chemically induced
  • Fibrosarcoma / diagnosis
  • Fibrosarcoma / veterinary*
  • Male
  • Soft Tissue Neoplasms / chemically induced
  • Soft Tissue Neoplasms / diagnosis
  • Soft Tissue Neoplasms / veterinary*
  • Thorax / pathology
  • Vaccination / adverse effects
  • Vaccination / veterinary*
  • Viral Vaccines / adverse effects*


  • Viral Vaccines