[Efficacy and tolerance of aniracetam in elderly patients with primary or secondary mental deterioration]

Riv Neurol. 1991 May-Jun;61(3):92-6.
[Article in Italian]


The study was carried out on 60 patients (mean age 69.9 +/- 10.3 years) suffering from slight-moderate brain pathology primary or secondary to vascular forms. Patients were treated with 1500 mg/day per os of Aniracetam or placebo. Drug efficiency evaluation was performed utilizing the following psychometric tests: Blessed Scale, figures repetition test, Benton test, Corsi test, Rey test, Pieron test, phrases construction test, verbal fluency test. They were carried out during basal visit after two and four month treatment. In Aniracetam treated group the score showed a significant improving during the first and second control. In placebo treated group no change statistically considerable happened in any test. Aniracetam has proved to be a useful drug in slight-moderate brain decay treatment of the elderly.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Aged, 80 and over
  • Dementia / blood
  • Dementia / drug therapy*
  • Dementia / psychology
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Pyrrolidinones / therapeutic use*


  • Pyrrolidinones
  • aniracetam