Recurrent implantation failure: definition

J Assist Reprod Genet. 2007 Jul;24(7):284-7. doi: 10.1007/s10815-007-9147-4. Epub 2007 Aug 3.


Purpose: An attempt to define recurrent implantation failure.

Methods: Literature review.

Results: Numerous definitions of recurrent implantation failure exist. The complexity and redundancy of the process of implantation makes a single definition difficult to determine.

Conclusion: Each center must establish a definition of recurrent implantation failure based upon the data from that center. The definition of RIF used in our program requires the transfer of > or = 8, 8-cell stage embryos or > or = 5 blastocyst embryos.

Publication types

  • Review

MeSH terms

  • Abortion, Habitual / etiology*
  • Embryo Implantation*
  • Female
  • Fertilization in Vitro*
  • Humans
  • Recurrence
  • Treatment Failure