Low-carbohydrate nutrition and metabolism

Am J Clin Nutr. 2007 Aug;86(2):276-84. doi: 10.1093/ajcn/86.2.276.

Abstract

The persistence of an epidemic of obesity and type 2 diabetes suggests that new nutritional strategies are needed if the epidemic is to be overcome. A promising nutritional approach suggested by this thematic review is carbohydrate restriction. Recent studies show that, under conditions of carbohydrate restriction, fuel sources shift from glucose and fatty acids to fatty acids and ketones, and that ad libitum-fed carbohydrate-restricted diets lead to appetite reduction, weight loss, and improvement in surrogate markers of cardiovascular disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Cardiovascular Diseases / epidemiology
  • Diet, Carbohydrate-Restricted* / adverse effects
  • Dietary Carbohydrates / metabolism*
  • Exercise
  • Humans
  • Ketone Bodies / metabolism
  • Nutritional Status
  • Risk Factors
  • Weight Loss

Substances

  • Dietary Carbohydrates
  • Ketone Bodies