Methaemoglobinaemia causing progressive dyspnoea and cyanosis during treatment of Pneumocystis jirovecii pneumonia

Int J STD AIDS. 2007 Aug;18(8):577-8. doi: 10.1258/095646207781439720.

Abstract

An HIV-infected man became increasingly breathless and cyanosed while receiving clindamycin and primaquine treatment for Pneumocystis jirovecii pneumonia. He was found to have 11.4% methaemoglobinaemia and recovered with conservative management.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / adverse effects*
  • Anti-Bacterial Agents / therapeutic use
  • Clindamycin / therapeutic use
  • Cyanosis / etiology
  • Dyspnea / etiology
  • Humans
  • Male
  • Methemoglobinemia / chemically induced
  • Methemoglobinemia / complications*
  • Pneumocystis carinii / pathogenicity
  • Pneumonia, Pneumocystis / drug therapy*
  • Primaquine / adverse effects*
  • Primaquine / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Clindamycin
  • Primaquine