Resin bonding using an all-etch or self-etch adhesive to enamel after carbamide peroxide and/or CPP-ACP treatment

Aust Dent J. 2007 Jun;52(2):133-7. doi: 10.1111/j.1834-7819.2007.tb00478.x.


Background: Limited evidence exists regarding the effect of carbamide peroxide and casein phosphopeptide amorphous calcium phosphate (CPP-ACP) on composite-enamel bonding. Microshear bond strengths, using either a total-etch or self-etching adhesive, to enamel treated with carbamide peroxide and/or CPP-ACP were investigated.

Materials and methods: Twenty-six extracted human third molars were sectioned into four parts, each being allocated into one of the four groups (n=26): bleach (Polanight, 16% carbamide peroxide), CPP-ACP (GC Tooth Mousse), bleach and then CPP-ACP, or untreated (control). The surfaces were bonded with a total-etch bonding system (Single Bond) or a self-etching primer system (Clearfil SE Bond) and tested using a microshear test.

Results: A significant difference in bond strength was found between bonding systems. SE Bond showed the highest bond strength to untreated enamel (p < 0.05). The microshear bond strength of SE Bond decreased when the enamel was treated with carbamide peroxide, CPP-ACP or both (p < 0.05). Only combined use of carbamide peroxide and CPP-ACP significantly affected microshear bond strength with Single Bond.

Conclusion: These findings suggest the shear bond strength of resin to enamel using a self-etching priming adhesive may be affected if the enamel is treated with a bleaching agent or CPP-ACP.

Publication types

  • Comparative Study

MeSH terms

  • Acid Etching, Dental / methods*
  • Bisphenol A-Glycidyl Methacrylate / chemistry
  • Carbamide Peroxide
  • Caseins / pharmacology*
  • Composite Resins / chemistry*
  • Dental Bonding*
  • Dental Enamel / drug effects
  • Dental Enamel / ultrastructure*
  • Dental Materials / chemistry
  • Drug Combinations
  • Humans
  • Materials Testing
  • Oxidants / pharmacology*
  • Peroxides / pharmacology*
  • Resin Cements / chemistry
  • Shear Strength
  • Stress, Mechanical
  • Tooth Bleaching / methods*
  • Urea / analogs & derivatives*
  • Urea / pharmacology


  • Caseins
  • Clearfil SE Bond
  • Composite Resins
  • Dental Materials
  • Drug Combinations
  • Oxidants
  • Peroxides
  • Resin Cements
  • casein phosphopeptide-amorphous calcium phosphate nanocomplex
  • single bond
  • Carbamide Peroxide
  • Bisphenol A-Glycidyl Methacrylate
  • Urea