Investigating cellular stress responses--a multidisciplinary approach from basic science to therapeutics--report on the EuroSciCon (European Scientific Conferences) meeting

Cell Stress Chaperones. Summer 2007;12(2):106-11. doi: 10.1379/csc-261r.1.

Abstract

The meeting on "Investigating cellular stress responses--a multidisciplinary approach from basic science to therapeutics" was held in London on 13 October 2006. The purpose of this 1-day meeting was to bring together European scientists investigating the immune biology of stress proteins and their potential clinical applications. The main topics included: the role of heat shock proteins (Hsps) in bacterial infections; the role of Hsps with a molecular mass of about 70 kDa in cancer therapy and in prediction of the clinical outcome following allogeneic hematopoietic stem cell transplantation; the quality and duration of stress as a danger signal for the initiation of a stress response; the mechanism of Hsp-protein interaction; and Hsp export from tumor cells in secretory granules.

Publication types

  • Congress

MeSH terms

  • Animals
  • Bacterial Infections / metabolism
  • ErbB Receptors / genetics
  • HSP70 Heat-Shock Proteins / genetics
  • HSP70 Heat-Shock Proteins / metabolism
  • Heat-Shock Response*
  • Hematopoietic Stem Cell Transplantation
  • Humans
  • Immunity, Innate / immunology
  • Protein Transport
  • Transcriptional Activation / genetics

Substances

  • HSP70 Heat-Shock Proteins
  • ErbB Receptors