Dramatic progression of skin involvement in systemic sclerosis after the appearance of anti-Scl70 antibody: a case report

Paola Caramaschi; Alessandro Volpe; Antonio Carletto; Lisa Maria Bambara; Domenico Biasi

doi:10.1007/s00296-007-0434-2

Dramatic progression of skin involvement in systemic sclerosis after the appearance of anti-Scl70 antibody: a case report

Rheumatol Int. 2008 Feb;28(4):385-6. doi: 10.1007/s00296-007-0434-2. Epub 2007 Aug 10.

Authors

Paola Caramaschi¹, Alessandro Volpe, Antonio Carletto, Lisa Maria Bambara, Domenico Biasi

Affiliation

¹ Dipartimento di Medicina Clinica e Sperimentale, Università di Verona, Policlinico G.B. Rossi, P.le Scuro, 37134 Verona, Italy. paola.caramaschi@azosp.vr.it

PMID: 17690886
DOI: 10.1007/s00296-007-0434-2

Abstract

The authors describe a young man suffering from systemic sclerosis who showed a dramatic progression of skin involvement after the appearance of anti-Scl70 antibody.

Publication types

Case Reports

MeSH terms

Adult
Autoantibodies / blood*
DNA Topoisomerases, Type I
Disease Progression
Humans
Immunosuppressive Agents / therapeutic use
Male
Microscopic Angioscopy
Nuclear Proteins / immunology*
Scleroderma, Systemic / complications
Scleroderma, Systemic / immunology*
Scleroderma, Systemic / pathology
Skin Ulcer / drug therapy
Skin Ulcer / immunology*
Skin Ulcer / pathology
Treatment Outcome

Substances

Autoantibodies
Immunosuppressive Agents
Nuclear Proteins
Scl 70 antigen, human
DNA Topoisomerases, Type I