Clinical presentation of sarcoidosis in a mixed population in the middle east

Respir Med. 2007 Nov;101(11):2284-8. doi: 10.1016/j.rmed.2007.06.025. Epub 2007 Aug 13.

Abstract

Background: Regional and ethnic differences in the presentation and prognosis of sarcoidosis have been reported.

Objectives: To describe and compare the clinical characteristics of sarcoidosis among Arabs and South East Asians (SEA).

Methods: Data on patients with sarcoidosis were collected retrospectively 1983-1995 and prospectively 1995-2003.

Results: A total of 142 patients, 57% females and 80% Arabs, were identified. The age at onset shows the majority of cases (45%) among Arab males occur at 30-39 years, 60% of Arab females occur at 40-59 years and 61% of SEA males occur at 40-49 years. The most common symptoms were cough 77.5%, dyspnoea 54.2%, fever 31.0%, arthralgia 19%, uveitis 14.8%, erythema nodosum 14.8%, and lymphadenopathy 12%. The radiological stage at presentation was stage 0,2.1%, I,44.4%, II,42.3%, and III,11.3%. The frequency of either stage 0 or I was higher among SEA (62%) compared to Arabs 42.5%, p=0.05.

Conclusion: There is a peak of sarcoidosis among Arab males at 30-39 years, Arab females at 40-59 years and SEA males at 40-49 years. Arab patients presented more frequently with either stage II or III compared to SEA who usually present with stage 0 or I.

MeSH terms

  • Adult
  • Age Distribution
  • Age of Onset
  • Arabs*
  • Asians*
  • Female
  • Humans
  • Kuwait / epidemiology
  • Male
  • Middle Aged
  • Prospective Studies
  • Retrospective Studies
  • Sarcoidosis / diagnosis
  • Sarcoidosis / epidemiology*
  • Sarcoidosis / ethnology
  • Sex Distribution