Intake of vitamin A-rich foods and lung cancer risk in Taiwan: with special reference to garland chrysanthemum and sweet potato leaf consumption

Asia Pac J Clin Nutr. 2007;16(3):477-88.


A case-control study was conducted to investigate the association between the consumption of local common foods that are rich in vitamin A and the risk of lung cancer in Taiwan. A total of 301 incident lung cancer cases, 602 hospital controls, and 602 neighborhood controls were recruited. The consumption of 13 food items and vitamin supplements was estimated by use of a food frequency questionnaire. The conditional logistic regression models were used to estimate the adjusted odds ratios (AOR) and 95% confidence intervals (CI) for lung cancer risk with each control group as reference by adjustment of covariates. A reduced risk for lung cancer was found to be associated with increased intakes of vitamin A, alpha-carotene, and beta-carotene from 13 food items. More servings of vegetables (AOR for the highest versus the lowest quartile = 0.67-0.70, 95% CI = 0.42-1.08, (plinear trend )= 0.04), garland chrysanthemum (AOR for the highest versus the lowest tertile = 0.58-0.74, 95% CI = 0.37-1.14, (plinear trend )<= 0.04) and sweet potato leaves (AOR for the highest versus the lowest tertile = 0.43-0.65, 95% CI = 0.28-0.96, (plinear trend )<= 0.03) were associated with the reduced risk for lung cancer. In conclusion, higher consumption of vitamin A-rich vegetables, especially garland chrysanthemum and sweet potato leaves might provide potential protection from lung cancer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Case-Control Studies
  • Chrysanthemum / chemistry*
  • Confidence Intervals
  • Diet*
  • Female
  • Food Analysis
  • Humans
  • Ipomoea batatas / chemistry*
  • Logistic Models
  • Lung Neoplasms / epidemiology*
  • Lung Neoplasms / etiology
  • Male
  • Middle Aged
  • Nutrition Assessment*
  • Odds Ratio
  • Plant Leaves / chemistry
  • Risk Factors
  • Smoking / adverse effects
  • Surveys and Questionnaires
  • Taiwan / epidemiology
  • Vitamin A / administration & dosage*


  • Vitamin A