Synovial sarcoma of the sellar region

Neuro Oncol. 2007 Oct;9(4):454-9. doi: 10.1215/15228517-2007-029. Epub 2007 Aug 17.

Abstract

Primary sarcomas of the sellar region are uncommon, although a wide variety have been reported. To date, no cases of primary synovial sarcoma have been described as occurring at this site. We report an immunohistochemically and molecular genetically confirmed primary synovial sarcoma involving the sellar/parasellar region and cavernous sinus in an adult male. Subtotal resection and radiosurgery proved to be efficacious. The spectrum of primary sellar region sarcomas is summarized.

Publication types

  • Case Reports

MeSH terms

  • Cavernous Sinus / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / pathology
  • Neurosurgical Procedures
  • Oncogene Proteins, Fusion
  • Radiosurgery
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sarcoma, Synovial / genetics
  • Sarcoma, Synovial / pathology*
  • Sarcoma, Synovial / therapy*
  • Sella Turcica / pathology*
  • Skull Base Neoplasms / genetics
  • Skull Base Neoplasms / pathology*
  • Skull Base Neoplasms / therapy*
  • Translocation, Genetic

Substances

  • Oncogene Proteins, Fusion
  • SYT-SSX fusion protein