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Review
. 2007 Sep;9(5):373-7.
doi: 10.1007/s11912-007-0050-z.

Therapy-related acute myelogenous leukemia and myelodysplastic syndrome

Gautam Borthakur  1 , And Elihu E Estey
Affiliations
Review

Therapy-related acute myelogenous leukemia and myelodysplastic syndrome

Gautam Borthakur et al. Curr Oncol Rep. 2007 Sep.

Abstract

Therapy-related acute myelogenous leukemia and myelodysplastic syndrome (t-AML/MDS) are increasing in prevalence with aging of the population and improved survival of patients treated with chemotherapy or radiotherapy for other malignancies. Research focused on the pathogenesis of t-AML/MDS will provide insight into the pathogenesis of de novo AML/MDS. Participation in clinical trials should be encouraged for this patient population because results with available treatment options are clearly suboptimal.

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