RXLR effectors of plant pathogenic oomycetes

Curr Opin Microbiol. 2007 Aug;10(4):332-8. doi: 10.1016/j.mib.2007.04.005. Epub 2007 Aug 17.


Oomycetes are a phylogenetically distinct group of organisms that include some of the most devastating plant pathogens. Recent characterization of four oomycete Avr genes revealed that they encode effector proteins with a common modular structure, including a N-terminal conserved RXLR motif. Several lines of evidence initially indicated, with support from more recent works, that these Avr proteins are secreted by the pathogen and then translocated into the host cell during infection. In addition to elucidating the machinery required for host-cell transport, future works remain to determine the myriad virulence functions of oomycete RXLR effector proteins.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Algal Proteins / chemistry*
  • Amino Acid Motifs
  • Oomycetes / chemistry*
  • Oomycetes / pathogenicity*
  • Plant Diseases / microbiology*
  • Virulence


  • Algal Proteins