Vocal fold medialization in children: injection laryngoplasty, thyroplasty, or nerve reinnervation?

Arch Otolaryngol Head Neck Surg. 2007 Aug;133(8):767-71. doi: 10.1001/archotol.133.8.767.

Abstract

Objective: To review surgical interventions for pediatric unilateral vocal fold immobility (UVFI).

Design: Retrospective medical chart review.

Setting: Two tertiary academic centers.

Patients: All children who underwent vocal fold medialization for dysphonia, with or without aspiration, from January 2004 to September 2006.

Interventions: Injection laryngoplasty, ansa cervicalis-recurrent laryngeal nerve anastomosis, or thyroplasty.

Main outcome measures: Age, sex, intervention, etiology, time from onset of UVFI to surgery, subjective success in improving voice, subjective duration of improvement, and complications.

Results: Twenty-seven procedures were performed in 15 patients (mean age, 10.6 years). Nineteen injection laryngoplasties, 3 thyroplasties (1 bilateral), 2 ansa cervicalis-recurrent laryngeal nerve reinnervation procedures, 1 adduction arytenoidopexy, and 1 cricothyroid joint subluxation were performed. Causes of UVFI included thoracic surgery in 6 cases (40%), prolonged intubation in 4 (26%), central nervous system neoplasm in 3 (20%), unknown etiology in 1 (7%), and anoxic brain injury in 1 (7%). The mean duration from onset of symptoms to treatment was 47 months. There was 1 surgical complication (postoperative aspiration pneumonia following thyroplasty while the patient was under local anesthesia). Parents reported a satisfactory outcome in all cases.

Conclusions: Injection laryngoplasty, thyroplasty, and nerve reinnervation can be performed in pediatric patients with good outcomes and an acceptable safety profile. This article describes the experiences of 2 institutions with phonosurgery for UVFI in children and provides insight into the advantages and disadvantages of each procedure. Prospective studies, with validated quality-of-life measurements, are needed to greater clarify the role of different types of phonosurgery in children with UVFI.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Anastomosis, Surgical / methods
  • Brain Stem Neoplasms / complications
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Hypoxia, Brain / complications
  • Injections
  • Interpersonal Relations
  • Male
  • Otorhinolaryngologic Surgical Procedures / methods*
  • Quality of Life / psychology
  • Recurrent Laryngeal Nerve / physiology*
  • Retrospective Studies
  • Severity of Illness Index
  • Social Behavior
  • Thyroid Gland / surgery*
  • Transplantation, Homologous*
  • Vocal Cord Paralysis / etiology*
  • Vocal Cord Paralysis / physiopathology
  • Vocal Cord Paralysis / therapy*