Genome sequence of Streptococcus mutans bacteriophage M102

FEMS Microbiol Lett. 2007 Oct;275(1):130-8. doi: 10.1111/j.1574-6968.2007.00873.x. Epub 2007 Aug 15.


Bacteriophage M102 is a lytic phage specific for serotype c strains of Streptococcus mutans, a causative agent of dental caries. In this study, the complete genome sequence of M102 was determined. The genome is 31,147 bp in size and contains 41 ORFs. Most of the ORFs encoding putative phage structural proteins show similarity to those from bacteriophages from Streptococcus thermophilus. Bioinformatic analysis indicated that the M102 genome contains an unusual lysis cassette, which encodes a holin and two lytic enzymes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Genome, Viral / genetics*
  • Molecular Sequence Data
  • Open Reading Frames / genetics
  • Proteome / genetics
  • Streptococcus Phages / genetics*
  • Streptococcus Phages / ultrastructure
  • Streptococcus mutans / virology*


  • Proteome

Associated data

  • GENBANK/AM749121