[Study on antioxidative activities of Psidium guajava Linn leaves extracts]

Wei Sheng Yan Jiu. 2007 May;36(3):298-300.
[Article in Chinese]


Objective: To study the antioxidative activities of the extracts from Psidium guajava Linn leaves (PGL).

Methods: The PGL was submersed with distilled water, 65% ethanol and 95% ethanol respectively. The 3 extracts were obtained after the solutions were filtered, concentrated and dried. The scavenging rate to hydroxyl radicals and inhibiting rate to lipid peroxidation were analyzed for the 3 extracts. Their contents of total flavonoids were determined by ultraviolet spectrophotometry, and the components of total flavonoids were primarily identified by high performance liquid chromatography (HPLC) and ultraviolet-visible absorption spectrometry (UV).

Results: The extracts from distilled water, 65% ethanol and 95% ethanol respectively showed effects on scavenging hydroxyl radicals and inhibiting lipid peroxidation in the dose-dependent manner, had 50% effective concentration (EC50) on scavenging hydroxyl radicals of 0.63, 0.47 and 0.58g/L, had EC50 on inhibiting lipid peroxidation of 0.20, 0.035, 0.18g/L and had total flavonoids contents of 3.28, 30.71 and 55.98g/kg respectively.

Conclusion: The aquatic and the ethanol extracts from PGL possess the potential antioxidative activities in the study. The flavonoids may be one of their antioxidative components.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antioxidants / pharmacology*
  • Flavonoids / analysis
  • Flavonoids / pharmacology
  • Lipid Peroxides / metabolism
  • Male
  • Mice
  • Plant Extracts / pharmacology*
  • Plant Leaves / chemistry*
  • Psidium / chemistry*


  • Antioxidants
  • Flavonoids
  • Lipid Peroxides
  • Plant Extracts