Splenectomy: a new treatment option for ALL tumors expressing Hox-11 and a means to test the stem cell hypothesis of cancer in humans

Leukemia. 2007 Oct;21(10):2192-4. doi: 10.1038/sj.leu.2404927. Epub 2007 Aug 16.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bone Marrow Cells / metabolism
  • Cell Lineage
  • Gene Expression Regulation, Leukemic*
  • Hematopoietic Stem Cells / cytology*
  • Hematopoietic Stem Cells / metabolism
  • Homeodomain Proteins / biosynthesis*
  • Humans
  • Mice
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / metabolism*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / surgery*
  • Proto-Oncogene Proteins / biosynthesis*
  • Spleen / metabolism
  • Splenectomy / methods*
  • Stem Cells / metabolism

Substances

  • Homeodomain Proteins
  • Proto-Oncogene Proteins
  • TLX1 protein, human