Safety profile of treatment in diabetic peripheral neuropathic pain

Pain Med. 2007 Sep:8 Suppl 2:S43-9. doi: 10.1111/j.1526-4637.2007.00351.x.

Abstract

New treatment options for diabetic peripheral neuropathic pain (DPNP) have recently been developed, including two Food and Drug Administration (FDA) approved agents, duloxetine and pregabalin. As clinicians face a broader spectrum of efficacious treatments, side-effect profiles play an increasingly important role in the development of a pain management regimen. In this article we review the safety profile of agents commonly used in the treatment of DPNP.

Publication types

  • Review

MeSH terms

  • Administration, Topical
  • Analgesics / therapeutic use
  • Anesthetics, Local / administration & dosage
  • Anesthetics, Local / therapeutic use
  • Anticonvulsants / adverse effects*
  • Anticonvulsants / therapeutic use*
  • Antidepressive Agents / adverse effects*
  • Antidepressive Agents / therapeutic use*
  • Antidepressive Agents, Second-Generation / therapeutic use
  • Antidepressive Agents, Tricyclic / therapeutic use
  • Capsaicin / administration & dosage
  • Capsaicin / therapeutic use
  • Cyclohexanols / therapeutic use
  • Diabetic Neuropathies / complications*
  • Duloxetine Hydrochloride
  • Humans
  • Pain / drug therapy*
  • Pain / etiology*
  • Pregabalin
  • Thiophenes / adverse effects*
  • Thiophenes / therapeutic use*
  • Venlafaxine Hydrochloride
  • gamma-Aminobutyric Acid / adverse effects
  • gamma-Aminobutyric Acid / analogs & derivatives*
  • gamma-Aminobutyric Acid / therapeutic use

Substances

  • Analgesics
  • Anesthetics, Local
  • Anticonvulsants
  • Antidepressive Agents
  • Antidepressive Agents, Second-Generation
  • Antidepressive Agents, Tricyclic
  • Cyclohexanols
  • Thiophenes
  • Pregabalin
  • gamma-Aminobutyric Acid
  • Venlafaxine Hydrochloride
  • Duloxetine Hydrochloride
  • Capsaicin