Abstract
New treatment options for diabetic peripheral neuropathic pain (DPNP) have recently been developed, including two Food and Drug Administration (FDA) approved agents, duloxetine and pregabalin. As clinicians face a broader spectrum of efficacious treatments, side-effect profiles play an increasingly important role in the development of a pain management regimen. In this article we review the safety profile of agents commonly used in the treatment of DPNP.
MeSH terms
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Administration, Topical
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Analgesics / therapeutic use
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Anesthetics, Local / administration & dosage
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Anesthetics, Local / therapeutic use
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Anticonvulsants / adverse effects*
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Anticonvulsants / therapeutic use*
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Antidepressive Agents / adverse effects*
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Antidepressive Agents / therapeutic use*
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Antidepressive Agents, Second-Generation / therapeutic use
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Antidepressive Agents, Tricyclic / therapeutic use
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Capsaicin / administration & dosage
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Capsaicin / therapeutic use
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Cyclohexanols / therapeutic use
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Diabetic Neuropathies / complications*
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Duloxetine Hydrochloride
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Humans
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Pain / drug therapy*
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Pain / etiology*
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Pregabalin
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Thiophenes / adverse effects*
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Thiophenes / therapeutic use*
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Venlafaxine Hydrochloride
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gamma-Aminobutyric Acid / adverse effects
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gamma-Aminobutyric Acid / analogs & derivatives*
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gamma-Aminobutyric Acid / therapeutic use
Substances
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Analgesics
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Anesthetics, Local
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Anticonvulsants
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Antidepressive Agents
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Antidepressive Agents, Second-Generation
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Antidepressive Agents, Tricyclic
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Cyclohexanols
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Thiophenes
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Pregabalin
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gamma-Aminobutyric Acid
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Venlafaxine Hydrochloride
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Duloxetine Hydrochloride
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Capsaicin