Microbicides development program, Tanzania-baseline characteristics of an occupational cohort and reattendance at 3 months

Sex Transm Dis. 2007 Sep;34(9):638-43. doi: 10.1097/OLQ.0b013e3180325120.


Objectives: To determine baseline characteristics of an occupational cohort of women in Mwanza City, Tanzania, and factors associated with reattendance at 3 months, in preparation for a microbicide trial.

Study design: One thousand five hundred seventy-three women aged 16-54 years working in food outlets and recreational facilities were enrolled, interviewed, and examined at community-based reproductive health clinics, provided specimens for HIV/STI and pregnancy testing, and attended 3 monthly clinical follow-up.

Results: Baseline prevalence of HIV was 25.5%; pregnancy 9.7%; herpes simplex virus type-2 74.6%; active syphilis 10.2%, bacterial vaginosis 52.6%; gonorrhea 5.5%; chlamydia 5.9%; and trichomoniasis 12.3%. Reattendance at 3 months was 74.1% and was higher in older women, less mobile women, and in those who received an HIV-negative result at enrollment.

Conclusions: Baseline characteristics of this occupational group suggest their suitability for microbicide trials. A screening round, locally appropriate informed consent procedures, and effective community tracing may help reduce losses to follow-up in such settings.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Anti-Infective Agents / administration & dosage*
  • Cohort Studies
  • Community Health Centers / statistics & numerical data*
  • Female
  • Food Industry
  • Humans
  • Middle Aged
  • Occupations / statistics & numerical data*
  • Patient Compliance*
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Complications, Infectious / etiology
  • Pregnancy Complications, Infectious / prevention & control*
  • Prevalence
  • Program Development
  • Recreation
  • Sexually Transmitted Diseases / epidemiology*
  • Sexually Transmitted Diseases / etiology
  • Sexually Transmitted Diseases / prevention & control*
  • Socioeconomic Factors
  • Tanzania / epidemiology


  • Anti-Infective Agents