Impaired glucose tolerance is associated with postganglionic sudomotor impairment

Clin Auton Res. 2007 Aug;17(4):231-3. doi: 10.1007/s10286-007-0426-z. Epub 2007 Aug 23.


We compared quantitative sudomotor axon-reflex test responses in persons with normal and impaired glucose tolerance (IGT). Responses were significantly impaired in those with IGT, which may be indicative of early distal small fiber neuropathy.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aged
  • Axons
  • Female
  • Glucose Intolerance / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Reflex
  • Sweat Glands / innervation*
  • Sweating*
  • Sympathetic Fibers, Postganglionic / physiopathology*