[Photodynamic therapy of lid basal cell carcinomas in a 13-year-old patient with Gorlin Goltz syndrome]

Klin Monbl Augenheilkd. 2007 Aug;224(8):670-3. doi: 10.1055/s-2007-963439.
[Article in German]


Background: Gorlin Goltz syndrome is a rare, autosomal dominant inherited disease that is characterised by multiple basal cell carcinomas (BCC) including the periorbital region and eye lids. We report a severe infantile manifestation with lid involvement treated by photodynamic therapy (PDT).

Patient: A 13-year-old boy with Gorlin Goltz syndrome presented with multiple confluent BCC on both eye lids and the skin of neck and trunk. Multiple bilateral periorbital confluent and surgically not removable BCC were treated by topical PDT.

Results: Numerous superficial BCC were successfully treated by photodynamic therapy with remarkable cosmetic results.

Conclusion: In cases of numerous confluent and surgically not removable BCC, PDT represents an effective therapy. Frequent monitoring is necessary to maintain the clinical outcome.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adolescent
  • Basal Cell Nevus Syndrome / drug therapy*
  • Basal Cell Nevus Syndrome / pathology*
  • Carcinoma, Basal Cell / drug therapy*
  • Carcinoma, Basal Cell / pathology*
  • Eyelid Neoplasms / drug therapy*
  • Eyelid Neoplasms / pathology*
  • Humans
  • Male
  • Photochemotherapy / methods*
  • Treatment Outcome