Abstract
Impulse control disorders (ICDs), including pathological gambling, trichotillomania, kleptomania and others, have been conceptualized to lie along an impulsive-compulsive spectrum. Recent data have suggested that these disorders may be considered addictions. Here, we review the genetic and neuropathological bases of the impulse control disorders and consider the disorders within these non-mutually exclusive frameworks.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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Animals
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Decision Making
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Disruptive, Impulse Control, and Conduct Disorders / etiology*
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Disruptive, Impulse Control, and Conduct Disorders / genetics
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Dopamine / physiology
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Endorphins / physiology
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Genetics, Population
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Glutamic Acid / physiology
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Humans
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Impulsive Behavior
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Prefrontal Cortex / physiology
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Reward
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Stress, Psychological / complications
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Substance-Related Disorders / etiology*
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Substance-Related Disorders / genetics
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gamma-Aminobutyric Acid / physiology
Substances
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Endorphins
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Glutamic Acid
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gamma-Aminobutyric Acid
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Dopamine