Revving the engine: signal transduction fuels T cell activation

Immunity. 2007 Aug;27(2):173-8. doi: 10.1016/j.immuni.2007.07.008.


For initiation of an immune response, resting T cells must reprogram their metabolism. Continuing the "From the Field" series (see Editorial [2007] 26, 131), Jones and Thompson draw attention to the importance of metabolism during T cell activation and consider how this process is regulated by receptor-mediated signal transduction.

Publication types

  • Comment

MeSH terms

  • Animals
  • Glycolysis
  • Humans
  • Lymphocyte Activation*
  • Mitochondria / metabolism
  • Protein Biosynthesis
  • Signal Transduction*
  • T-Lymphocytes / immunology*
  • T-Lymphocytes / metabolism