An integrated view of quantitative trait variation using tomato interspecific introgression lines

Curr Opin Genet Dev. 2007 Dec;17(6):545-52. doi: 10.1016/j.gde.2007.07.007. Epub 2007 Aug 27.


Resolving natural phenotypic variation into genetic and molecular components is a major objective in biology. Over the past decade, tomato interspecific introgression lines (ILs), each carrying a single 'exotic' chromosome segment from a wild species, have exposed thousands of quantitative trait loci (QTL) affecting plant adaptation, morphology, yield, metabolism, and gene expression. QTL for fruit size and sugar composition were isolated by map-based cloning, while others were successfully implemented in marker-assisted breeding programs. More recently, integrating the multitude of IL-QTL into a single database has unraveled some unifying principles about the architecture of complex traits in plants.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Breeding*
  • Chromosome Mapping
  • Chromosomes, Plant
  • Genetic Markers
  • Genomics
  • Lycopersicon esculentum / genetics*
  • Phenotype
  • Quantitative Trait Loci*


  • Genetic Markers