Antibacterial activity of Chamomilla recutita oil extract against Helicobacter pylori

Phytother Res. 2008 Feb;22(2):252-3. doi: 10.1002/ptr.2243.


The antibacterial activity of an oil extract of Chamomilla recutita flowers against Helicobacter pylori (H. pylori) was evaluated by the agar dilution method using Colombia agar with 10% sheep blood, an inoculum of McFarland 0.5 and incubation in an anaerobic atmosphere at 37 degrees C for 3 days. The oil extract was prepared by olive oil extraction of Chamomilla recutita flowers using rotary pulsation. The MIC(90) (minimal inhibitory concentration) and MIC(50) were 125 mg/mL and 62.5 mg/mL, respectively. It was shown that the Chamomilla recutita oil extract inhibited the production of urease by H. pylori. In addition, it was found that the morphological and fermentative properties of H. pylori were affected by application of the Chamomilla recutita oil extract.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology*
  • Helicobacter pylori / drug effects*
  • Helicobacter pylori / growth & development
  • Helicobacter pylori / metabolism
  • Matricaria / chemistry*
  • Microbial Sensitivity Tests
  • Olive Oil
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology*
  • Plant Oils / chemistry
  • Urease / metabolism


  • Anti-Bacterial Agents
  • Olive Oil
  • Plant Extracts
  • Plant Oils
  • Urease