[Use of enterosorption for correction of dyslipoproteinemias in patients with ischemic heart disease in geriatric practice]

Klin Med (Mosk). 1991 Jun;69(6):51-3.
[Article in Russian]

Abstract

Sixty patients with coronary heart disease, stable angina pectoris of functional class II and III and dislipoproteinemia (cholesterol greater than 6.5 mmol/l, triglycerides greater than 2.0 mmol/l, the atherogenic index greater than 3.5) were assigned to two groups. 40 patients received enterosorbent (high-porous, small-spherical fraction of CKH carbon). 20 control subjects were treated with placebo. The patients age ranged from 60 to 74. The treatment course lasted for 4 weeks. Evaluation of the treatment results showed that total cholesterol dropped by 20%, triglycerides by 27%, apoB by 32%, apoB-containing lipoproteins by 20%; there were positive changes in circulation, clinical status (in 60% of cases), exercise tolerance (by 12%). Control patients did not present any noticeable shifts. Thus, enterosorption proved an effective modality of dyslipoproteinemia correction in coronary patients of advanced age.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • English Abstract

MeSH terms

  • Aged
  • Charcoal / administration & dosage
  • Cholesterol, LDL / blood*
  • Cholesterol, VLDL / blood*
  • Coronary Disease / blood*
  • Enterosorption*
  • Female
  • Humans
  • Hypercholesterolemia / therapy*
  • Male
  • Middle Aged
  • Placebos

Substances

  • Cholesterol, LDL
  • Cholesterol, VLDL
  • Placebos
  • SKN hemosorbents
  • Charcoal