Reversible optic neuropathy due to metronidazole

Clin Exp Ophthalmol. 2007 Aug;35(6):585-6. doi: 10.1111/j.1442-9071.2007.01537.x.


Metronidazole is a little known cause of drug-induced optic neuropathy. We report a patient who developed progressive visual loss after an 8-month course of Metronidazole. Electrophysiology confirmed a bilateral optic neuropathy. Her vision improved dramatically with cessation of the drug.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Anti-Infective Agents / adverse effects*
  • Electrophysiology
  • Female
  • Humans
  • Metronidazole / adverse effects*
  • Optic Nerve Diseases / chemically induced*
  • Optic Nerve Diseases / physiopathology
  • Vision Disorders / chemically induced
  • Vision Disorders / physiopathology
  • Visual Acuity


  • Anti-Infective Agents
  • Metronidazole