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Clinical Trial
. 2007 Sep;6(3):189-94.
doi: 10.1111/j.1473-2165.2007.00329.x.

The Use of Light-Emitting Diode Therapy in the Treatment of Photoaged Skin

Affiliations
Clinical Trial

The Use of Light-Emitting Diode Therapy in the Treatment of Photoaged Skin

Fabien Baez et al. J Cosmet Dermatol. .

Abstract

Background: Light-emitting diode (LED) therapy is an increasingly popular methodology for the treatment of sun damage. Combination use of light wavelengths reported to stimulate collagen synthesis and accelerate fibroblast-myofibroblast transformation may display a composite rejuvenative effect.

Objective: To clinically assess reduction in sun damage signs following a 5-week course of LED therapy and to assess subject's perception of the treatment.

Methods: Thirteen subjects with wrinkles or fine lines in the periorbital and nasolabial region and those presenting Glogau scale photodamage grade II-III received nine 20-min duration light treatments using the Omnilux LED system. The treatments combined wavelengths of 633 and 830 nm at fluences of 126 and 66 J/cm(2), respectively. Sun-damage reduction was assessed at 6, 9, and 12 weeks by clinical photography and patient satisfaction scores.

Results: The majority of subjects displayed "moderate" (50%) or "slight" (25%) response to treatment at investigator assessment. Treatment of the periorbital region was reported more effective than the nasolabial region. At 12-week follow-up, 91% of subjects reported improved skin tone, and 82% reported enhanced smoothness of skin in the treatment area.

Conclusion: Good response to LED therapy has been shown in this modest sample. Larger trials are needed to assess optimum frequency of light treatments and overall treatment time.

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